[. . . ] SterisonicTM GxP Selection
Feature H2O2 Vapor Decontamination SafeCell UV Decontamination
TM
CO2 Incubators
MCO19AIC(UVH) Standard Standard Standard N/A MCO19AIC(UV) Optional Standard Standard N/A MCO19AIC Optional Optional Standard N/A MCO19M(UVH) Standard Standard Standard Standard
CO2 /O2 Incubators
MCO19M(UV) Optional Standard Standard Standard MCO19M Optional Optional Standard Standard
Single Beam, Dual Detector IR CO2 Sensor Oxygen Concentration Control, Zirconia Control
Product Applications
The combination of SterisonicTM GxP incubator performance functions permit use with confidence in high-value cell protocols among hard-to-grow cell lines, cells highly sensitive to contamination, ultra-sensitive media and reagents, or protocols that require a strict isolation and decontamination between processes. These include but are not limited to: · Stem cell research · Autologous tissue regeneration and regenerative medicine · In vitro fertilization1 · Genomic and proteomic expression · Esoteric plant and amphibian cell culture · Hypersensitive and transgenic cell culture · Low media volume microplate work
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MCO-19AIC(UVH) Designed for use with a variety of standard cell culture vessels and protocols.
· Interior components and adjustable shelves are configured for easy access, in situ decontamination and flexible arrangement for a variety of applications. · Four adjustable shelves are included, standard; maximum shelf capacity is 15 shelves.
MCO-19M Multi-Gas Incubator, Oxygen and CO2 Control
· Ideal for in vitro fertilization (IVF), genetic research, regenerative medicine and other protocols that require CO2 and sub-ambient (hypoxic) or above-ambient oxygen control. · Cabinet based on MCO-19 platform with inCu safeTM copper-enriched stainless steel chamber, continuous contamination control, patented D. H. A. [. . . ] · Inventory shelves and brackets are formed from polished copper-enriched stainless steel, removable without tools, and can remain inside the incubator during the H2O2 decontamination cycle or autoclaved separately if desired.
Elevated Humidity, Low Water Level Warning
To avoid cell culture desiccation, the SANYO SterisonicTM GxP CO2 incubator maintains ~95% RH at 37°C. · Humidification is achieved by a combined forced-air and natural evaporation method enhanced by the Direct Heat and Air JacketTM base heater, and protected by an optical water level indicator to warn of low water in the removable humidity pan. · The humidity pan removes easily for regular cleaning and refill. The optical sensor returns to position and the SafeCellTM UV lamp destroys any contaminants introduced during the process. · For the H2O2 in situ decontamination cycle the humidity pan is repositioned against the chamber wall to eliminate the need for separate autoclaving.
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SterisonicTM GxP Control System
Intelligent Interface Through Integrated LCD Control with Graphical Display--The SterisonicTM GxP incubator is managed by an integrated microprocessor controller with LCD graphical display to simplify all incubator functions. Stable temperature and humidity conditions are achieved through a combination of performance systems supervised by the controller complete with alarm, programming, calibration and diagnostic protocols. Control Features
· The SterisonicTM GxP control and information center includes an intuitive pop-up menu, high resolution LCD for inputs, outputs and performance at-a-glance. · Multi-point data logging offers pushbutton graphical display. An optional PC interface permits remote transmission for GMP/GLP protocols as required. · Selected performance histories can be acquired in graphical format for easy interpretation. · Precise PID logic controls and adjusts to all temperature and CO2 setpoints and alarm parameters. A two-stage regulator from the supply cylinder to the incubator is required; see Accessories. · Cabinet based on MCO-19 platform with inCu safeTM copper-enriched stainless steel chamber, continuous contamination control, patented D. H. A. multi-point, air-jacketed temperature control system, elevated relative humidity with integral water-level sensor.
inCu saFeTM Construction for Germicidal Protection
SANYO offers exclusive use of inCu saFeTM copper-enriched stainless steel alloy interior surfaces within a technical design created to eliminate contamination sources and to mitigate the effect of airborne contaminates introduced through normal use. · Selected to provide natural germicidal protection without rust or corrosion, inCu saFeTM expresses a natural germicidal attribute to inhibit the growth of molds, fungi, mycoplasma and bacteria. · All interior components, including the air management plenum, shelf supports, humidity pan and blower wheel assembly are easily removable without tools if required. · During the H2O2 decontamination cycle interior components can be repositioned within the chamber for in situ decontamination. · When components are removed, all interior surfaces are exposed for conventional wipe down. · Large curve corners and electropolished surfaces are easy to clean. · Pass thru ports accommodate probes or instrumentation leads as required for specialized cell culture protocols. Each chamber includes a port positioned in the interior, rear wall, upper left, with dual, non-VOC silicone stoppers inside and outside the cabinet for added protection.
MCO-19M Series Multi-Gas Performance O2 Control System
In addition to precise CO2 control, the MCO-19M Series incubator delivers exceptional O2 control in support of cell culture processes which require belowambient or above-ambient oxygen levels. These include in vitro fertilization (IVF), gene research, regenerative medicine and emerging applications that are sensitive to oxygen levels other than ambient. [. . . ] 4, adjustable.
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SterisonicTM GxP Series Cell Culture Incubators
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SterisonicTM GxP CO2/O2 Series Specifications
SterisonicTM GxP CO2/O2 Incubators
Description Single Chamber Model Number Dual Chamber Model Number Major Operating Systems H2O2 Decontamination System SafeCell UV System
TM
MCO-19M(UVH) MCO-38M(UVH)
MCO-19M(UV) MCO-38M(UV)
MCO-19M MCO-38M
Standard Standard Standard Standard Standard Standard
Optional Standard Standard Standard Standard Standard
Optional Optional Standard Standard Standard Standard
Single Beam, Dual Detector IR CO2 Sensor inCu saFeTM Copper Enriched Stainless Steel Interior LCD Graphical Controller/Display, Door Mounted Direct Heat, AirTM (DHA) Air Jacket Decontamination H2O2 Decontamination System Interior UV Lamp, Programmable, Ozone Free Copper Enriched Stainless Steel Interior with Germicidal Protection Environmental Performance Temperature Control Range Temperature Control Uniformity Deviation CO2 Control Range and Deviation CO2 Sensor Platform CO2 Calibration O2 Control Range and Deviation O2 Sensor Platform Airflow Interior Humidity Control, Monitoring, Alarm Temperature and CO2 Control Display Data Acquisition Communications
Vaporization in situ Standard Standard
Optional Standard Standard
Optional Optional Standard
+5ºC above ambient to 50°C (in a 5ºC to 35ºC ambient) ±0. 25ºC (in 25ºC ambient, setting 37ºC, 5% CO2, no load) 0% to 20%, ±0. 15% in 25ºC ambient, setting 37ºC, 5% CO2, no load Ceramic based, single beam, dual wavelength measurement of actual vs. Single point zero automatic; semi-automatic one point span at reference (optional). 1-18%, 22-80%, ±0. 2% in 25ºC ambient, setting 37ºC, no load Zirconia sensor, microprocessor P. I. D. 95%RH @ 37°C through evaporation via DHATM heating system; reflective optical low water sensor.
P. I. D. , setpoint resolution 0. 1% and 0. 1°C Alphanumeric LCD digital display messaging. [. . . ]